Point of Care
Point of Care

Sepsis: Transform
Risk Stratification
at the bedside

A deadly and costly crisis

Common

~1 in 3 patients who die in the hospital have sepsis1

Costly

Financial burden on hospitals totaling over 6% of hospital costs2

Consequential

Leading cause of mortality with 700 000 deaths in the EU every year2

Sepsis mortality — one hour makes all the difference

An updated, evidence-based bundle from the Surviving Sepsis Campaign (SSC), released in 2018, emphasizes expediency of care to improve survival.

2018 SSC Hour-1 Bundle:
Measure lactate level. Re-measure if initial lactate is >2 mmol/L 
Obtain blood cultures prior to administration of antibiotics 
Administer broad-spectrum antibiotics 
Rapidly administer 30 ml/kg crystalloid for hypotension or lactate ≥4 mmol/L 
Apply vasopressors if patient is hypotensive during or after fluid resuscitation to maintain MAP ≥65 mm Hg 
  • Lactate-guided resuscitation is associated with significantly reduced mortality4
  • Yet only 53% of clinicians order lactate with blood culture for patients with sepsis3
  • When lactate is ordered, long turnaround times have been identified as a barrier to bundle compliance4

8%

Every hour sepsis treatment is delayed, risk of death increases by up to 8%4
Solutions

i-STAT CG4+ — Expediting Risk Stratification to optimize acuity-based care

When every minute counts, i-STAT CG4+ improves care team efficiency, coordination, and communication─quickly guiding resources to those who need it most.

In clinical studies, i-STAT CG4+ has been shown to significantly improve ED efficiency and quality.

  • Reduced door-to-lactate result time by 72%5
  • Reduced ED care time (arrival-to-disposition decision) by 11%6 
  • Provided a cost-effective means to identify patients benefitting from early resuscitation7
Related Items

cartridge-icon-small.png Lactate and sepsis testing with cg4+

i-stat-icon-small.png i-STAT handheld

case-study-small.png Case study: Reaching goals with first-time use of i-STAT at a busy emergency department

Want more information about how your organization
can achieve sepsis care transformation?

Request more info

 Back to Challenges

References

1. CDC Sepsis Fact Sheet.
2. Hand Hygiene Day its in your hands prevent sepsis in health care, WHO Europe Website. www.euro.who.int/en/health-topics   
3. Advisory Board Sepsis Research Report. 
4. Levy MM, Evans LE, Rhodes A. 
5. Singer AJ, Taylor M, LeBlanc D et al. 2014. 
6. Singer AJ, Taylor M, LeBlanc D et al. 2018. 
7. Ward MJ, Self WH, Singer A et al.

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